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Article

Cortical migration defects in mice expressing A-RAF from the B-RAF locus.

Molecular and cellular biology - 1 Oct 2006

Camarero Guadalupe, Tyrsin Oleg Yu, Xiang Chaomei, Pfeiffer Verena, Pleiser Sandra, Wiese Stefan, Götz Rudolf, Rapp Ulf R

Abstract excerpt

We have previously shown that mice lacking the protein kinase B-RAF have defects in both neural and endothelial cell lineages and die around embryonic day 12 (E12). To delineate the function of B-RAF in the brain, B-RAF KIN/KIN mice lacking B-RAF and expressing A-RAF under the control of the B-RAF locus were created. B-RAF KIN/KIN embryos displayed no vascular defects, no endothelial and neuronal apoptosis, or...

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Identifiers

PMID: 16980614
DOI: 10.1128/MCB.00424-06
PMCID: PMC1592881

Genes

KIN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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