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Article

Control of postnatal apoptosis in the neocortex by RhoA-subfamily GTPases determines neuronal density.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Mar 2010

Sanno Hitomi, Shen Xiao, Kuru Nilgün, Bormuth Ingo, Bobsin Kristin, Gardner Humphrey A R, Komljenovic Dorde, Tarabykin Victor, Erzurumlu Reha S, Tucker Kerry L

Abstract excerpt

Apoptosis of neurons in the maturing neocortex has been recorded in a wide variety of mammals, but very little is known about its effects on cortical differentiation. Recent research has implicated the RhoA GTPase subfamily in the control of apoptosis in the developing nervous system and in other tissue types. Rho GTPases are important components of the signaling pathways linking extracellular signals to the...

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Identifiers

PMID: 20335457
DOI: 10.1523/JNEUROSCI.3318-09.2010
PMCID: PMC2852171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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