Article
Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant.
Developmental neurobiology - 1 Aug 2016
Daviaud Nicolas, Chen Karen, Huang Yong, Friedel Roland H, Zou Hongyan
Abstract excerpt
Mammalian cortical expansion is tightly controlled by fine-tuning of proliferation and differentiation of neural progenitors in a region-specific manner. How extrinsic cues interface with cell-intrinsic programs to balance proliferative versus neurogenic decisions remains an unsolved question. We examined the function of Semaphorin receptors Plexin-B1 and -B2 in corticogenesis by generating double mutants,...
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