Article
Significance of MHC class II haplotypes and IgG Fc receptors in SLE.
Springer seminars in immunopathology - 1 Oct 2006
Hirose Sachiko, Jiang Yi, Nishimura Hiroyuki, Shirai Toshikazu
Abstract excerpt
Systemic lupus erythematosus (SLE) is a systemic antibody-mediated autoimmune disease that develops under the control of multiple susceptibility genes. Genetic studies in murine and human SLE have identified several chromosomal intervals that contain candidate susceptibility genes. However, the ultimate identification of the genes and their roles in disease process need much further investigation. Spontaneous...
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