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Article

Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus.

Clinical & developmental immunology - 1 Jan 2012

Relle Manfred, Schwarting Andreas

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies against nuclear antigens and a systemic inflammation that can damage a broad spectrum of organs. SLE patients suffer from a wide variety of symptoms, which can affect virtually almost any tissue. As lupus is difficult to diagnose, the worldwide prevalence of SLE can only be roughly estimated to...

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Identifiers

PMID: 22761632
DOI: 10.1155/2012/584374
PMCID: PMC3385965

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Source receipt: pubmed, retrieved 7 Sept 2026.

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