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Article

FcγRIIB, FcγRIIIB, and systemic lupus erythematosus

1 Jan 2010

Abstract excerpt

The autoimmune disease systemic lupus erythematosus (SLE) is characterized by the deposition of immune complexes in organs such as the kidney. This occurs as a result of multiple immunological abnormalities, including the production of high levels of autoantibody and dysregulated handling of immune complexes. Receptors for the Fc portion of IgG are critically involved in immune complex handling and clearance and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 20146709
DOI: 10.1111/j.1749-6632.2009.05132.x

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