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Article

Fc receptor genes and the systemic lupus erythematosus diathesis.

Autoimmunity - 1 Dec 2007

Brown Elizabeth E, Edberg Jeffrey C, Kimberly Robert P

Abstract excerpt

Fc receptors represent a distinct group of hematopoeitic cell surface glycoproteins that have a characterized role in affecting the efficiency of the mononuclear phagocyte system to clear IgG immune complexes. Functional genetic variations in this family of receptors have been identified as heritable susceptibility factors for SLE and lupus nephritis across diverse populations. In this review, we describe the...

Topics

Animals
Antigen-Antibody Complex
Epistasis, Genetic
Genetic Predisposition to Disease
Humans
Inflammation
Linkage Disequilibrium
Lupus Erythematosus, Systemic
Phagocytes
Receptors, Fc

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18075791
DOI: 10.1080/08916930701763710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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