Article
Fc receptor genes and the systemic lupus erythematosus diathesis.
Autoimmunity - 1 Dec 2007
Brown Elizabeth E, Edberg Jeffrey C, Kimberly Robert P
Abstract excerpt
Fc receptors represent a distinct group of hematopoeitic cell surface glycoproteins that have a characterized role in affecting the efficiency of the mononuclear phagocyte system to clear IgG immune complexes. Functional genetic variations in this family of receptors have been identified as heritable susceptibility factors for SLE and lupus nephritis across diverse populations. In this review, we describe the...
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