Article
[The ts phenotype of reisolates from children inoculated with live cold-adapted influenza vaccine type A].
Voprosy virusologii - 1 Jan 2000
Medvedeva T E, Romanova Iu R, Gushchina M I, Rudenko L G, Gendon Iu Z, Aleksandrova G I, Klimov A I
Abstract excerpt
Using mutants of fowl plague virus (FRV) which have single temperature-sensitive (ts) mutations in some genes, an analysis was carried out on reisolates from children of 3-6 years, vaccinated with a monovaccine from recombinant strains of influenza type A virus. The recombinants were obtained by crossing of current epidemic strains of subtypes A (HINI) and a (H3N2) with the cold-adapted (XA) ts-donor of...
Topics
- Antigens, Viral
- Child
- Child, Preschool
- Cold Temperature
- Epitopes
- Genes, Viral
- Humans
- Influenza A virus
- Influenza Vaccines
- Mutation
- Phenotype
