Article
[The temperature sensitivity of epidemic influenza A viruses as a marker of immunogenicity of reassortant vaccinal strains].
Voprosy virusologii - 1 Jan 2000
Kiseleva I V, Grigor'eva E P, Naĭkhin A N, Ivanova V V, Larionova N V, Donina S A, Litvinova O M, Aleksandrova G I, Rudenko L G
Abstract excerpt
The influence of ts-phenotype of epidemic viruses and of cold-adapted (CA) reassortant vaccines' strains, appropriately prepared, produced on the human immunogenicity was under investigation. A widespread variability of epidemic viruses' thermal sensitivity sign was established. It was shown that the CA reassortant vaccine strains, obtained through crossbreeding of attenuation donors and of thermally resistant...
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