[The temperature sensitivity of epidemic influenza A viruses as a marker of immunogenicity of reassortant vaccinal strains].

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Article

[The temperature sensitivity of epidemic influenza A viruses as a marker of immunogenicity of reassortant vaccinal strains].

Voprosy virusologii - 1 Jan 2000

Kiseleva I V, Grigor'eva E P, Naĭkhin A N, Ivanova V V, Larionova N V, Donina S A, Litvinova O M, Aleksandrova G I, Rudenko L G

Abstract excerpt

The influence of ts-phenotype of epidemic viruses and of cold-adapted (CA) reassortant vaccines' strains, appropriately prepared, produced on the human immunogenicity was under investigation. A widespread variability of epidemic viruses' thermal sensitivity sign was established. It was shown that the CA reassortant vaccine strains, obtained through crossbreeding of attenuation donors and of thermally resistant...

Topics

Administration, Intranasal
Adolescent
Antibodies, Viral
Child
Cold Temperature
Humans
Influenza A virus
Influenza Vaccines
Influenza, Human
Phenotype
Reassortant Viruses
Vaccination
Vaccines, Attenuated

Source

Open in PubMed

Identifiers

PMID: 12945203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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