Article
[Mutations in the genes coding for hemagglutinin and neuraminidase in cold-adapted variants of the influenza virus A/Leningrad/134/57 (H2N2)].
Voprosy virusologii - 1 Jan 2000
Medvedeva T E, Kudriavtseva V K, Zhikhareva I V, Romashkina V V, Aleksandrova G I, Klimov A I
Abstract excerpt
An analysis of ts-mutations in the genomes of native and cold-adapted variants of influenza A/Leningrad/134/57 (H2N2) virus based on the use of fowl plague virus ts mutants was carried out. The recombination test was done by the conventional method in chick embryo fibroblast culture (genes PB2, P...
Topics
- Adaptation, Physiological
- Animals
- Chick Embryo
- Cold Temperature
- Genes, Viral
- Genetic Code
- Genetic Variation
- Hemagglutinins, Viral
- Influenza A Virus, H2N2 Subtype
- Influenza A virus
- Influenza Vaccines
- Mice
- Mice, Inbred CBA
- Mutation
- Neuraminidase
- Recombination, Genetic
- Vaccines, Attenuated
- Virus Replication