Article
[Genetic techniques for the production of influenza vaccines (author's transl)].
Annali Sclavo; rivista di microbiologia e di immunologia - 1 Jan 2000
Teti G
Abstract excerpt
Influenza mortality and morbidity underscore the need for a more immunogenic influenza vaccine with a shorter production time. Techniques of rapid derivation of mutants and of genetic recombination appear promising in producing vaccines, responsive to major antigenic shifts of influenza virus. "Cold" adapted, inhibitor resistant and temperature sensitive mutants have all proven safe and effective in adults as...
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