Article
[Peculiarity of reassortment of current wild type influenza viruses with master donor viruses for live influenza vaccine].
Voprosy virusologii - 1 Jan 2000
Kiseleva I V, Bazhenova E A, Larionova N V, Fedorova E A, Dubrovina I A, Isakova-Sivak I N, Rudenko L G
Abstract excerpt
The live attenuated influenza vaccine (LAIV) currently licensed in Russia consists of the reassortant viruses with hemagglutinin (HA) and neuraminidase (NA) gene segments from the circulating wild-type viruses and the six internal protein-encoding gene segments from cold-adapted master donor viruses (MDV) A/Leningrad/134/17/57 (H2N2) or B/USSR/60/69. Presently, only classical reassortment technique is approved...
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