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Article

[Changes in the genetic properties of a viral population and the selection of ts-mutants in persistent influenza virus infection].

Voprosy virusologii - 1 Jan 2000

Medvedeva M N, Aron R A, Golubev D B

Abstract excerpt

Comparative study of genetic properties of the original influenza A/Victoria/35/72 virus (the inhibitor-sensitive variant) and persisting viruses (PV) isolated at different intervals (from 9 to 158 days) after infection with this virus of MDCK cell culture revealed that in the course of development of persistent infection (PI) there occurred progressive selection of temperature-sensitive (ts) mutants. In parallel...

Topics

Animals
Antigens, Viral
Cell Line
Dogs
Hemagglutinins, Viral
Influenza A virus
Mutation
Orthomyxoviridae Infections
Selection, Genetic
Temperature
Time Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Interference

Virus Cultivation

Source

Identifiers

PMID: 6528573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6528573-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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