Article
[Changes in the genetic properties of a viral population and the selection of ts-mutants in persistent influenza virus infection].
Voprosy virusologii - 1 Jan 2000
Medvedeva M N, Aron R A, Golubev D B
Abstract excerpt
Comparative study of genetic properties of the original influenza A/Victoria/35/72 virus (the inhibitor-sensitive variant) and persisting viruses (PV) isolated at different intervals (from 9 to 158 days) after infection with this virus of MDCK cell culture revealed that in the course of development of persistent infection (PI) there occurred progressive selection of temperature-sensitive (ts) mutants. In parallel...
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