Article
State-dependent block of BK channels by synthesized shaker ball peptides.
The Journal of general physiology - 1 Oct 2006
Li Weiyan, Aldrich Richard W
Abstract excerpt
Crystal structures of potassium channels have strongly corroborated an earlier hypothetical picture based on functional studies, in which the channel gate was located on the cytoplasmic side of the pore. However, accessibility studies on several types of ligand-sensitive K(+) channels have suggested that their activation gates may be located near or within the selectivity filter instead. It remains to be...
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