Article
Gated access to the pore of a voltage-dependent K+ channel.
Neuron - 1 Jul 1997
Liu Y, Holmgren M, Jurman M E, Yellen G
Abstract excerpt
Voltage-activated K+ channels are integral membrane proteins that open or close a K(+)-selective pore in response to changes in transmembrane voltage. Although the S4 region of these channels has been implicated as the voltage sensor, little is known about how opening and closing of the pore is accomplished. We explored the gating process by introducing cysteines at various positions thought to lie in or near the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.