Article
Novel IL10 gene family associations with systemic juvenile idiopathic arthritis.
Arthritis research & therapy - 1 Jan 2006
Fife Mark S, Gutierrez Ana, Ogilvie Emma M, Stock Carmel J W, Samuel Jane M, Thomson Wendy, Mack Lisa F, Lewis Cathryn M, Woo Patricia
Abstract excerpt
Juvenile idiopathic arthritis (JIA) is the most common cause of chronic childhood disability and encompasses a number of disease subgroups. In this study we have focused on systemic JIA (sJIA), which accounts for approximately 11% of UK JIA cases. This study reports the investigation of three members of the IL10 gene family as candidate susceptibility loci in children with sJIA. DNA from 473 unaffected controls...
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