Article
Association of IL-17A and IL-10 Polymorphisms with Juvenile Idiopathic Arthritis in Finnish Children.
International journal of molecular sciences - 30 Jul 2024
Möttönen Milja, Teräsjärvi Johanna, Rahikkala Heidi, Kvist Sonja, Mertsola Jussi, He Qiushui
Abstract excerpt
To analyze the role of interleukin IL-17A and IL-10 polymorphisms in susceptibility to juvenile idiopathic arthritis (JIA), 98 Finnish children and adolescents with JIA were studied. Data from the 1000 Genomes Project, consisting of 99 healthy Finns, served as the controls. The patients were analyzed for four IL-17A and three IL-10 gene-promoter polymorphisms, and the serum IL-17A, IL-17F, IL-10, and IL-6 levels...
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