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Article

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA).

PloS one - 1 Jan 2012

Omoyinmi Ebun, Forabosco Paola, Hamaoui Raja, Bryant Annette, Hinks Anne, Ursu Simona, Wedderburn Lucy R, Thomson Wendy, Lewis Cathryn M, Woo Patricia

Abstract excerpt

BACKGROUND: The cytokine IL-10 and its family members have been implicated in autoimmune diseases and we have previously reported that genetic variants in IL-10 were associated with a rare group of diseases called juvenile idiopathic arthritis (JIA). The aim of this study was to fine map genetic variants within the IL-10 cytokine family cluster on chromosome 1 using linkage disequilibrium (LD)-tagging single...

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Share to Arthritis, Juvenile
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23094074
DOI: 10.1371/journal.pone.0047673
PMCID: PMC3475696

Genes

FCAMR
MAPKAPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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