Article
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.
Annals of the rheumatic diseases - 1 May 2017
Ombrello Michael J, Arthur Victoria L, Remmers Elaine F, Hinks Anne, Tachmazidou Ioanna, Grom Alexei A, Foell Dirk, Martini Alberto, Gattorno Marco, Özen Seza, Prahalad Sampath, Zeft Andrew S, Bohnsack John F, Ilowite Norman T, Mellins Elizabeth D, Russo Ricardo, Len Claudio, Hilario Maria Odete E, Oliveira Sheila, Yeung Rae S M, Rosenberg Alan M, Wedderburn Lucy R, Anton Jordi, Haas Johannes-Peter, Rosen-Wolff Angela, Minden Kirsten, Tenbrock Klaus, Demirkaya Erkan, Cobb Joanna, Baskin Elizabeth, Signa Sara, Shuldiner Emily, Duerr Richard H, Achkar Jean-Paul, Kamboh M Ilyas, Kaufman Kenneth M, Kottyan Leah C, Pinto Dalila, Scherer Stephen W, Alarcón-Riquelme Marta E, Docampo Elisa, Estivill Xavier, Gül Ahmet, Langefeld Carl D, Thompson Susan, Zeggini Eleftheria, Kastner Daniel L, Woo Patricia, Thomson Wendy
Abstract excerpt
OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a heterogeneous group of conditions unified by the presence of chronic childhood arthritis without an identifiable cause. Systemic JIA (sJIA) is a rare form of JIA characterised by systemic inflammation. sJIA is distinguished from other forms of JIA by unique clinical features and treatment responses that are similar to autoinflammatory diseases. However,...
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