Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila melanogaster fl(2)d gene is needed for the female-specific splicing of Sex-lethal RNA.

The EMBO journal - 1 Aug 1990

Granadino B, Campuzano S, Sánchez L

Abstract excerpt

In Drosophila melanogaster, sex determination and dosage compensation are under the control of the Sex-lethal (Sxl) gene. We have identified a gene, female-lethal-2-d (fl(2)d), located in the second chromosome, that interacts with Sxl. fl(2)d homozygous clones, induced during the larval stage of fl(2)d/+ females, develop male structures instead of female ones. fl(2)d homozygous females hypertranscribe their two X...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Drosophila melanogaster
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Recombination, Genetic

Share to RNA Splicing

Share to Transcription, Genetic

Share to X Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 1695150
DOI: 10.1002/j.1460-2075.1990.tb07441.x
PMCID: PMC552292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila melanogaster fl(2)d gene is needed for the female-specific splicing of Sex-lethal RNA.PMID 1695150Read ↗

Evidence of a dual function in fl(2)d, a gene needed for Sex-lethal expression in Drosophila melanogaster.Semantic proximity Read ↗

flex, an X-linked female-lethal mutation in Drosophila melanogaster controls the expression of Sex-lethal.Semantic proximity Read ↗

Genetic and molecular analysis of new female-specific lethal mutations at the gene Sxl of Drosophila melanogaster.Semantic proximity Read ↗

Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.Semantic proximity Read ↗

An N-terminal truncation uncouples the sex-transforming and dosage compensation functions of sex-lethal.Semantic proximity Read ↗

Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila.Semantic proximity Read ↗

Induction of female Sex-lethal RNA splicing in male germ cells: implications for Drosophila germline sex determination.Semantic proximity Read ↗

Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product.Semantic proximity Read ↗

Evolution of the Drosophila feminizing switch gene Sex-lethal.Semantic proximity Read ↗

Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila.Semantic proximity Read ↗

The translation initiation factor eIF4E regulates the sex-specific expression of the master switch gene Sxl in Drosophila melanogaster.Semantic proximity Read ↗

Mutations in the predicted aspartyl tRNA synthetase of Drosophila are lethal and function as dosage-sensitive maternal modifiers of the sex determination gene Sex-lethal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.