Article
Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila.
Genes & development - 15 Mar 1994
Palmer M J, Richman R, Richter L, Kuroda M I
Abstract excerpt
Dosage compensation in Drosophila occurs by a twofold increase in transcription per copy of X-linked genes in males (XY) compared with females (XX). msl-1 is one of four genes that are essential for dosage compensation in males, and MSL-1 protein is associated specifically with the male X chromos...
Topics
- Animals
- Blotting, Western
- Chromosome Mapping
- Crosses, Genetic
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Dosage
- Genes, Lethal
- Genotype
- Heterozygote
- Homozygote
- Larva
- Male
- Nuclear Proteins
- Sex Characteristics
- Transcription Factors