Article
Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila.
Genes & development - 15 Mar 1994
Palmer M J, Richman R, Richter L, Kuroda M I
Abstract excerpt
Dosage compensation in Drosophila occurs by a twofold increase in transcription per copy of X-linked genes in males (XY) compared with females (XX). msl-1 is one of four genes that are essential for dosage compensation in males, and MSL-1 protein is associated specifically with the male X chromosome. To explore the basis for the sex specificity of dosage compensation, we examined MSL-1 expression in males,...
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