Article
Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila.
Development (Cambridge, England) - 1 Feb 1995
Gorman M, Franke A, Baker B S
Abstract excerpt
In Drosophila, dosage compensation occurs by transcribing the single male X chromosome at twice the rate of each of the two female X chromosomes. This hypertranscription requires four autosomal male-specific lethal (msl) genes and is negatively regulated by the Sxl gene in females. Two of the msl...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Western
- Dosage Compensation, Genetic
- Drosophila
- Drosophila Proteins
- Female
- Gene Expression
- Genes, Insect
- Insect Hormones
- Male
- Models, Genetic
- Molecular Sequence Data
- Nuclear Proteins
- Phenotype
- RNA-Binding Proteins