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Article

Doublecortin is necessary for the migration of adult subventricular zone cells from neurospheres.

Molecular and cellular neurosciences - 1 Oct 2006

Ocbina Polloneal J, Dizon Maria L V, Shin Laura, Szele Francis G

Abstract excerpt

Mutations in human doublecortin (DCX) and knockdown of Dcx in rodents cause radial migration defects in the embryonic cerebral cortex. However, the brain phenotype of Dcx knockout mice is largely normal suggesting that Dcx is not necessary for most migration events. Adult subventricular zone (SVZ) cells migrate tangentially in the rostral migratory stream to the olfactory bulbs. Dcx is expressed in the SVZ but it...

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Source

Identifiers

PMID: 16931042
DOI: 10.1016/j.mcn.2006.06.014

Genes

DCX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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