Article
Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of neuronal migration disorder.
Nature medicine - 1 Jan 2009
Manent Jean-Bernard, Wang Yu, Chang Yoonjeung, Paramasivam Murugan, LoTurco Joseph J
Abstract excerpt
Disorders of neuronal migration can lead to malformations of the cerebral neocortex that greatly increase the risk of seizures. It remains untested whether malformations caused by disorders in neuronal migration can be reduced by reactivating cellular migration and whether such repair can decreas...
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