Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Doublecortin maintains bipolar shape and nuclear translocation during migration in the adult forebrain.

Nature neuroscience - 1 Jun 2006

Koizumi Hiroyuki, Higginbotham Holden, Poon Tiffany, Tanaka Teruyuki, Brinkman Brendan C, Gleeson Joseph G

Abstract excerpt

The ability of the mature mammalian nervous system to continually produce neuronal precursors is of considerable importance, as manipulation of this process might one day permit the replacement of cells lost as a result of injury or disease. In mammals, the anterior subventricular zone (SVZa) region is one of the primary sites of adult neurogenesis. Here we show that doublecortin (DCX), a widely used marker for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Cell Shape

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemotaxis

Share to Doublecortin Domain Proteins

Share to Doublecortin Protein

Share to Neurites

Share to Neuropeptides

Share to Prosencephalon

Source

Identifiers

PMID: 16699506
DOI: 10.1038/nn1704

Genes

DCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Doublecortin maintains bipolar shape and nuclear translocation during migration in the adult forebrain.PMID 16699506Read ↗

Doublecortin is necessary for the migration of adult subventricular zone cells from neurospheres.Semantic proximity Read ↗

Distinct Features of Doublecortin as a Marker of Neuronal Migration and Its Implications in Cancer Cell MobilitySemantic proximity Read ↗

Selective expression of doublecortin and LIS1 in developing human cortex suggests unique modes of neuronal movement.Semantic proximity Read ↗

Doublecortin is required in mice for lamination of the hippocampus but not the neocortex.Semantic proximity Read ↗

Separate progenitors for radial and tangential cell dispersion during development of the cerebral neocortex.Semantic proximity Read ↗

Ventral migration of early-born neurons requires Dcc and is essential for the projections of primary afferents in the spinal cord.Semantic proximity Read ↗

Genes that regulate neuronal migration in the cerebral cortex.Semantic proximity Read ↗

Magnetic resonance imaging and histological studies of corpus callosal and hippocampal abnormalities linked to doublecortin deficiency.Semantic proximity Read ↗

Doublecortin restricts neuronal branching by regulating tubulin polyglutamylationSemantic proximity Read ↗

Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration.Semantic proximity Read ↗

Alternative Splicing of Disabled-1 Controls Multipolar-to-Bipolar Transition of Migrating Neurons in the Neocortex.Semantic proximity Read ↗

Neuroblasts of the postnatal mammalian forebrain: their phenotype and fate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.