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Article

A nucleotide that enhances the charging of RNA minihelix sequence variants with alanine.

Biochemistry - 17 Apr 1990

Shi J P, Francklyn C, Hill K, Schimmel P

Abstract excerpt

We showed earlier that a single G3.U70 base pair within the amino acid acceptor helix is a major determinant of the identity of tRNA(Ala). In addition, we demonstrated that an RNA hairpin minihelix that recreates the 12 base pair acceptor-T psi C stem of tRNA(Ala) is also aminoacylated in a G3.U7...

Topics

Alanine-tRNA Ligase
Amino Acyl-tRNA Synthetases
Base Composition
Escherichia coli
Genetic Variation
Kinetics
RNA

Source

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Identifiers

PMID: 1692733
DOI: 10.1021/bi00467a005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1692733-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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