Article
Permutation of a pair of tertiary nucleotides in a transfer RNA.
Biochemistry - 7 Mar 1995
Hou Y M, Sterner T, Jansen M
Abstract excerpt
The tertiary nucleotides at positions 15 and 48 in a tRNA establish non-Watson-Crick hydrogen interactions that connect the dihydrouridine (D) loop with the variable loop and stabilize the "L"-shaped tRNA structure. Although the majority of tRNAs have G15.C48 or A15.U48, all of the 16 possible nucleotide pairs at positions 15 and 48 can be found in the existing cytoplasmic and mitochondrial tRNA sequences....
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