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Article

Functional evidence for indirect recognition of G.U in tRNA(Ala) by alanyl-tRNA synthetase.

Science (New York, N.Y.) - 12 Jan 1996

Gabriel K, Schneider J, McClain W H

Abstract excerpt

The structural features of the G.U wobble pair in Escherichia coli alanine transfer RNA (tRNA(Ala)) that are associated with aminoacylation by alanyl-tRNA synthetase (AlaRS) were investigated in vivo for wild-type tRNA(Ala) and mutant tRNAs with G.U substitutions. tRNA(Ala) with G.U, C.A, or G.A gave similar amounts of charged tRNA(Ala) and supported viability of E. coli lacking chromosomal tRNA(Ala) genes....

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Source

Identifiers

PMID: 8539617
DOI: 10.1126/science.271.5246.195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Functional evidence for indirect recognition of G.U in tRNA(Ala) by alanyl-tRNA synthetase.PMID 8539617Read ↗

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