Article
Surprising contribution to aminoacylation and translation of non-Watson-Crick pairs in tRNA.
Proceedings of the National Academy of Sciences of the United States of America - 21 Mar 2006
McClain William H
Abstract excerpt
Molecules of transfer RNA (tRNA) typically contain four stems composed of Watson-Crick (W-C) base pairs and infrequent mispairs such as G-U and A-C. The latter mispairs are fundamental units of RNA secondary structure found in nearly every class of RNA and are nearly isomorphic to W-C pairs. Therefore, they often substitute for G-C or A-U base pairs. The mispairs also have unique chemical, structural, and dynamic...
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