Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.

doi:10.1093/carcin/bgl135

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Article

Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.

Carcinogenesis - 1 Feb 2007

Goode Ellen L, Potter John D, Bamlet William R, Rider David N, Bigler Jeannette

Abstract excerpt

Exposures such as cigarette smoke and meat contain a variety of procarcinogens, which are thought to play a role in elevation of risk for colorectal polyps and/or cancer. These procarcinogens (including heterocyclic amines and polycyclic aromatic hydrocarbons) are metabolized by a variety of poly...

Topics

Adult
Aged
Carcinogens
Case-Control Studies
Colonic Polyps
Enzymes
Genetic Predisposition to Disease
Genetic Variation
Humans
Middle Aged
Risk Factors

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