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Article

Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.

Carcinogenesis - 1 Feb 2007

Goode Ellen L, Potter John D, Bamlet William R, Rider David N, Bigler Jeannette

Abstract excerpt

Exposures such as cigarette smoke and meat contain a variety of procarcinogens, which are thought to play a role in elevation of risk for colorectal polyps and/or cancer. These procarcinogens (including heterocyclic amines and polycyclic aromatic hydrocarbons) are metabolized by a variety of polymorphic enzymes including N-acetyltransferases, sulfotransferases, cytochrome P450 enzymes and epoxide hydrolase. We...

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Source

Identifiers

PMID: 16926176
DOI: 10.1093/carcin/bgl135

Genes

EPHX1
NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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