Article
The Drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferation.
Journal of cellular biochemistry - 1 Dec 2006
Zhou Guang-Qian, Zhang Youyi, Ferguson David J P, Chen Sa, Rasmuson-Lestander Asa, Campbell Frederick C, Watt Suzanne M
Abstract excerpt
Endolyn (CD164) is a sialomucin that regulates the proliferation, adhesion, and migration of human haematopoietic stem and progenitor cells. This molecule is predominately localized in endocytotic compartments, where it may contribute to endolysosomal biogenesis and trafficking. In order to more closely define the function of endolyn from an evolutionary view-point, we first analyzed endolyn orthologs in species...
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