Article
N-glycans mediate apical recycling of the sialomucin endolyn in polarized MDCK cells.
Traffic (Copenhagen, Denmark) - 1 Feb 2006
Potter Beth A, Weixel Kelly M, Bruns Jennifer R, Ihrke Gudrun, Weisz Ora A
Abstract excerpt
Apical and basolateral proteins are maintained within distinct membrane subdomains in polarized epithelial cells by biosynthetic and postendocytic sorting processes. Sorting of basolateral proteins in these processes has been well studied; however, the sorting signals and mechanisms that direct proteins to the apical surface are less well understood. We previously demonstrated that an N-glycan-dependent sorting...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
