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Article

Asrij maintains the stem cell niche and controls differentiation during Drosophila lymph gland hematopoiesis.

PloS one - 1 Jan 2011

Kulkarni Vani, Khadilkar Rohan J, Magadi Srivathsa S, Srivathsa M S, Inamdar Maneesha S

Abstract excerpt

Several signaling pathways control blood cell (hemocyte) development in the Drosophila lymph gland. Mechanisms that modulate and integrate these signals are poorly understood. Here we report that mutation in a conserved endocytic protein Asrij affects signal transmission and causes aberrant lymph gland hematopoiesis. Mammalian Asrij (Ociad1) is expressed in stem cells of the blood vascular system and is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22110713
DOI: 10.1371/journal.pone.0027667
PMCID: PMC3215734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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