Article
Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells.
Blood - 1 Mar 2007
Forde Sinead, Tye Britt Jorgensen, Newey Sarah E, Roubelakis Maria, Smythe Jon, McGuckin Colin P, Pettengell Ruth, Watt Suzanne M
Abstract excerpt
Hematopoietic stem cell/hematopoietic progenitor cell (HSC/HPC) homing to specific microenvironmental niches involves interactions between multiple receptor ligand pairs. Although CXCL12/CXCR4 plays a central role in these events, CXCR4 regulators that provide the specificity for such cells to lodge and be retained in particular niches are poorly defined. Here, we provide evidence that the sialomucin endolyn...
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