Article
Regulation of myoblast motility and fusion by the CXCR4-associated sialomucin, CD164.
The Journal of biological chemistry - 28 Mar 2008
Bae Gyu-Un, Gaio Ursula, Yang Youn-Joo, Lee Hye-Jin, Kang Jong-Sun, Krauss Robert S
Abstract excerpt
Myoblast fusion is fundamental to the development and regeneration of skeletal muscle. To fuse, myoblasts undergo cell-cell recognition and adhesion and merger of membranes between apposing cells. Cell migration must occur in advance of these events to bring myoblasts into proximity, but the factors that regulate myoblast motility are not fully understood. CD164 is a cell surface sialomucin that is targeted to...
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