Transcriptional regulation of early-response genes during polyomavirus infection.

doi:10.1128/JVI.64.5.2193-2201.1990

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Article

Transcriptional regulation of early-response genes during polyomavirus infection.

Journal of virology - 1 May 1990

Glenn G M, Eckhart W

Abstract excerpt

Infection of quiescent BALB/c 3T3 cells with polyomavirus leads to the biphasic accumulation of RNA from several early-response genes. The steady-state levels of RNA of c-fos, c-myc, and c-jun were detected at 0 to 1 and 12 to 30 h after infection but not at 6 h postinfection. Infections with mutant viruses suggest that in the context of a virus infection with other tumor (T) antigens present, large T and middle...

Topics

Animals
Cell Nucleus
Cell Transformation, Neoplastic
Cells, Cultured
Chloramphenicol O-Acetyltransferase
DNA Replication
DNA-Binding Proteins
Gene Expression Regulation, Viral
Mice
Mice, Inbred BALB C
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Plasmids

Polyomavirus

Promoter Regions, Genetic

Protein-Tyrosine Kinases

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-fos

Source

Open in PubMed Open full text

Identifiers

PMID: 1691311
DOI: 10.1128/JVI.64.5.2193-2201.1990
PMCID: PMC249379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1691311-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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