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Article

E1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcription.

Journal of virology - 1 Jun 1991

DePolo N J, Villarreal L P

Abstract excerpt

Polyomavirus (Py) DNA replication may be regulated to a low-level replication state in specific target cells in mice as well as in certain undifferentiated murine cell lines, such as embryocarcinoma (EC) cells. To investigate possible mechanisms by which such control may occur, we have examined the effects of E1A on Py DNA replication. Adenovirus E1A proteins repress transcriptional activation of various...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1851864
DOI: 10.1128/JVI.65.6.2921-2928.1991
PMCID: PMC240926

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Source receipt: pubmed, retrieved 7 Sept 2026.

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