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Article

Activation of Proto-Oncogenes: an Immediate Early Event in Human Cytomegalovirus Infection

2 Feb 1990

Abstract excerpt

A rapid increase in the RNA levels of the proto-oncogenes c-fos, c-jun, and c-myc was detected after human cytomegalovirus infection. Neither inactivation of viral infectivity with ultraviolet irradiation (with or without psoralen), nor inhibition of translation with cycloheximide or anisomycin adversely affected the enhanced expression of proto-oncogenes, even though these treatments substantially reduced or...

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PMID: 1689075
DOI: 10.1126/science.1689075

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