Article
Role of mouse polyomavirus late region in the control of viral DNA replication: a review.
Biochimie - 1 Jan 1995
Iacoangeli A, Melucci-Vigo G, Risuleo G, Santi E
Abstract excerpt
The genome of polyomaviruses is divided into two coding regions: the early and the late region. A relatively short regulatory sequence, encompassing the origin of viral DNA replication (ori), separates the two regions encoding the structural genes. In mouse polyomavirus (Py) in particular, the early DNA codes for three antigens: large, middle and small T-antigen (L-T, M-T and S-T, respectively). Large T antigen...
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