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Article

Frequent Alterations in the Expression of Serine/Threonine Kinases in Human Cancers

15 Aug 2006

Abstract excerpt

Protein kinases constitute a large family of regulatory enzymes involved in the homeostasis of virtually every cellular process. Subversion of protein kinases has been frequently implicated in malignant transformation. Within the family, serine/threonine kinases (STK) have received comparatively lesser attention, vis-a-vis tyrosine kinases, in terms of their involvement in human cancers. Here, we report a...

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PMID: 16912193
DOI: 10.1158/0008-5472.can-05-3489

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