Article
Kinase mutations in cancer: chinks in the enemy's armour?
Current opinion in oncology - 1 Jan 2006
Di Nicolantonio Federica, Bardelli Alberto
Abstract excerpt
PURPOSE OF REVIEW: Over the past few years, a revolution has transformed the oncology field. This revolution is characterized by two main features. The first is the introduction of the concept of individualized cancer therapy. The second is the development of drugs targeting molecules selectively altered in tumours. This review analyses these aspects by looking at the role that altered kinases and their...
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