Article

Differential expression of RSK4 transcript isoforms in cancer and its clinical relevance

2022-10-05

Abstract excerpt

RSK4 belongs to the p90 Ribosomal S6 Kinase family which lies downstream of the MAPK pathway. While we previously revealed this kinase to be a therapeutic target in lung and bladder cancers, there is conflicting evidence for its wider role in other cancer types. Indeed, RSK4 was instead suggested to be a tumour suppressor in colorectal and gastric cancers, and reports of its role in breast malignancies are contrad...

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Literature Corpus work: e6124f2c-2064-5a38-998a-033c1a66fbd8
DOI: 10.1101/2022.10.03.510581

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