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Article

Population-based and family-based designs to analyze rare variants in complex diseases.

Genetic epidemiology - 1 Jan 2011

Kazma Rémi, Bailey Julia N

Abstract excerpt

Genotyping of rare variants on a large scale is now possible using next-generation sequencing. Sample selection is a crucial step in designing the genetic study of a complex disease, and knowledge of the efficiency and limitations of population-based and family-based designs can help researchers make the appropriate choice. The nine contributions to Group 5 of Genetic Analysis Workshop 17 evaluate...

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Identifiers

PMID: 22128057
DOI: 10.1002/gepi.20648
PMCID: PMC3393851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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