Article
Haplotype association analysis of human disease traits using genotype data of unrelated individuals.
Genetical research - 1 Dec 2005
Tan Qihua, Christiansen Lene, Christensen Kaare, Bathum Lise, Li Shuxia, Zhao Jing Hua, Kruse Torben A
Abstract excerpt
Haplotype inference has become an important part of human genetic data analysis due to its functional and statistical advantages over the single-locus approach in linkage disequilibrium mapping. Different statistical methods have been proposed for detecting haplotype - disease associations using unphased multi-locus genotype data, ranging from the early approach by the simple gene-counting method to the recent...
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