Article
Definition and clinical importance of haplotypes.
Annual review of medicine - 1 Jan 2005
Crawford Dana C, Nickerson Deborah A
Abstract excerpt
Advances in genotyping and sequencing technologies, coupled with the development of sophisticated statistical methods, have afforded investigators novel opportunities to define the role of sequence variation in the development of common human diseases. At the forefront of these investigations is the use of dense maps of single-nucleotide polymorphisms (SNPs) and the haplotypes derived from these polymorphisms....
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