Article
Evaluating associations of haplotypes with traits.
Genetic epidemiology - 1 Dec 2004
Schaid Daniel J
Abstract excerpt
Haplotypes have played a major role in the study of highly-penetrant single-gene disorders, and recent evidence that the human genome has hot-spots and cold-spots for recombination have suggested that haplotype-based methods may play a key role in the study of common complex traits. This report reviews the motivation of using haplotypes for the study of the genetic basis of human traits, ranging from biologic...
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