Article
Association of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability.
Journal of virology - 1 Apr 1990
Kornbluth S, Cheng S H, Markland W, Fukui Y, Hanafusa H
Abstract excerpt
A number of mutants of polyomavirus middle T antigen (MTag) were constructed into replication-competent avian retroviruses. To assess the ability of these MTag variants to transform and to associate with the avian p60c-src and p62c-yes proto-oncogene products, we used these viruses to infect chic...
Topics
- Animals
- Antigens, Polyomavirus Transforming
- Cell Transformation, Viral
- Chickens
- Hemangioma
- Mutation
- Plasmids
- Polyomavirus
- Protein Binding
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-yes
- Proto-Oncogene Proteins pp60(c-src)
- Transfection
- src-Family Kinases
