Article
Association of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability.
Journal of virology - 1 Apr 1990
Kornbluth S, Cheng S H, Markland W, Fukui Y, Hanafusa H
Abstract excerpt
A number of mutants of polyomavirus middle T antigen (MTag) were constructed into replication-competent avian retroviruses. To assess the ability of these MTag variants to transform and to associate with the avian p60c-src and p62c-yes proto-oncogene products, we used these viruses to infect chicken embryo fibroblasts. We found that the ability of individual mutant MTags to associate with p62c-yes correlated well...
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