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Article

Generation of a large library of point mutations in polyoma middle T antigen.

Nucleic acids research - 25 Dec 1991

Druker B J, Roberts T M

Abstract excerpt

Polyoma middle T antigen (MTAg) transforms cells by associating with and activating a variety of intracellular proteins, including src family members and a phosphatidylinositol-3 kinase. In order to assist in the study of the relative importance of the various associated biochemical activities for transformation by polyomavirus MTAg, a library of MTAg mutants was constructed. Chemically mutagenized MTAg DNA was...

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Identifiers

PMID: 1662365
DOI: 10.1093/nar/19.24.6855
PMCID: PMC329320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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