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Article

Cigarette smoking, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma.

British journal of cancer - 7 Aug 2006

van Dijk B A C, Schouten L J, Oosterwijk E, Hulsbergen-van de Kaa C A, Kiemeney L A L M, Goldbohm R A, Schalken J A, van den Brandt P A

Abstract excerpt

We investigated whether smoking is associated with mutations in the Von Hippel-Lindau (VHL) gene in 337 cases of sporadic renal cell carcinoma (RCC) among 120 852 people followed for 11.3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations.

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Source

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Identifiers

PMID: 16892044
DOI: 10.1038/sj.bjc.6603281
PMCID: PMC2360644

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cigarette smoking, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma.PMID 16892044Read ↗

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