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Article

Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinomas.

Cancer letters - 1 Jul 1999

Yang K, Lindblad P, Egevad L, Hemminki K

Abstract excerpt

Frequent loss-of-function somatic mutations of the VHL gene have been detected in sporadic renal cell carcinoma (RCC), indicating that inactivation of the VHL gene plays a critical role in RCC. In this study, we collected 35 archived Swedish sporadic RCCs identified from an epidemiological study on occupational exposure and kidney cancer to test how well stored pathological specimens could be retrieved and...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 10454237
DOI: 10.1016/s0304-3835(99)00031-2

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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